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Lidbury PS, Korbut R, Vane JR

Research protocols may examine whether interventions that modulate the glutathione synthesis pathway can affect neuronal survival, protein aggregation (e.g., alpha-synuclein or amyloid-beta), or mitochondrial function in these non-human systems

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748 Inhibition of this pathway using the PAR1 antagonist vorapaxar has been shown to reduce the burden of senescent cells, offering a potential therapeutic strategy

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